Kevin Colclough Selected Research

Glucokinase

1/2021	Evaluation of pregnancy outcomes in women with GCK-MODY.
1/2020	Absence of Islet Autoantibodies and Modestly Raised Glucose Values at Diabetes Diagnosis Should Lead to Testing for MODY: Lessons From a 5-Year Pediatric Swedish National Cohort Study.
10/2017	The prevalence of monogenic diabetes in Australia: the Fremantle Diabetes Study Phase II.
1/2014	Prevalence of vascular complications among patients with glucokinase mutations and prolonged, mild hyperglycemia.
5/2011	Discovery of a novel site regulating glucokinase activity following characterization of a new mutation causing hyperinsulinemic hypoglycemia in humans.
11/2009	Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia.
8/2009	Identification of a novel beta-cell glucokinase (GCK) promoter mutation (-71G>C) that modulates GCK gene expression through loss of allele-specific Sp1 binding causing mild fasting hyperglycemia in humans.
9/2006	Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha (HNF1A) and 4 alpha (HNF4A) in maturity-onset diabetes of the young.

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Kevin Colclough Research Topics

Disease

20	Type 2 Diabetes Mellitus (MODY) 10/2022 - 09/2006
7	Mason-Type Diabetes 01/2021 - 09/2006
5	Hypoglycemia (Reactive Hypoglycemia) 08/2021 - 06/2008
5	Hyperglycemia 01/2020 - 08/2009
4	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2021 - 11/2016
3	Insulin Resistance 11/2020 - 01/2018
2	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 01/2020 - 01/2016
1	Intellectual Disability (Idiocy) 08/2021
1	Microcephaly 08/2021
1	Birth Weight (Birth Weights) 01/2021
1	Gestational Diabetes (Gestational Diabetes Mellitus) 11/2020
1	Diabetes Mellitus 11/2020
1	Congenital Hyperinsulinism 06/2020
1	Acanthosis Nigricans 05/2020
1	Hirsutism 05/2020
1	Insulinoma 01/2020
1	Gitelman Syndrome 09/2019
1	Lipodystrophy 01/2018
1	Proteinuria 01/2014
1	Hyperinsulinism (Hyperinsulinemia) 06/2008

Drug/Important Bio-Agent (IBA)

10	Insulin (Novolin)FDA Link 01/2022 - 09/2006
8	GlucokinaseIBA 01/2021 - 09/2006
5	Biomarkers (Surrogate Marker)IBA 10/2022 - 05/2013
5	Glucose (Dextrose)FDA LinkGeneric 08/2021 - 06/2008
4	AutoantibodiesIBA 01/2020 - 11/2016
4	C-PeptideIBA 01/2020 - 05/2013
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2017
2	Insulin ReceptorIBA 11/2020 - 05/2020
2	Diazoxide (Hyperstat)FDA Link 11/2020 - 06/2008
2	P-2 (P 2)IBA 01/2020 - 10/2016
2	AntigensIBA 01/2020 - 01/2017
2	DNA (Deoxyribonucleic Acid)IBA 10/2017 - 10/2017
2	Hepatocyte Nuclear Factor 1-alpha (Hepatocyte Nuclear Factor 1 alpha)IBA 05/2013 - 09/2006
2	NFI Transcription FactorsIBA 05/2013 - 09/2006
2	Transcription Factors (Transcription Factor)IBA 05/2013 - 09/2006
1	tRNA MethyltransferasesIBA 08/2021
1	TransferasesIBA 08/2021
1	Transfer RNA (tRNA)IBA 08/2021
1	Zinc Transporter 8IBA 01/2020
1	ElectrolytesIBA 09/2019
1	MagnesiumIBA 09/2019
1	Hemoglobins (Hemoglobin)IBA 01/2016
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2014
1	cyclo(Arg-Pro) (CI 4)IBA 01/2014
1	CreatinineIBA 05/2013
1	Protein Isoforms (Isoforms)IBA 01/2010
1	Hepatocyte Nuclear FactorsIBA 06/2008

Therapy/Procedure

3	Therapeutics 01/2021 - 06/2008
2	Glycemic Control 01/2020 - 10/2017
1	Injections 01/2021
1	Cesarean Section (Caesarean Section) 01/2021